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KMID : 0644120140270040043
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Journal of Oriental Gynecology
2014 Volume.27 No. 4 p.43 ~ p.56
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A Review on Clinical Studies of Herbal Treatment for Infertility Caused by Polycystic Ovary Syndrome -Focusing on Chinese Clinical Trials-
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Won An-Na
Choi Min-Sun
Kim Dong-Il
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Abstract
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Objectives: The purpose of this study is to review the trend of chinese clinical studies of herbal treatment for infertility caused by Polycystic Ovary Syndrome (PCOS).
Methods: We searched the clinical studies published from 1979 to 2013 through CAJ (Chinese Academic Journal) with keywords of “PCOS and 不孕” or “多囊卵 巢?合證 and 不孕”. We analyzed the intervention type of clinical studies. In addition, We re-searched randomized controlled trials (RCTs) published from 2009 to 2013, assessed the quality of RCTs using the Jadad Scale and reanalyzed the intervention type of RCTs.
Results: One hundred and seventeen clinical studies were finally selected. Clinical studies of herbal treatment for infertility caused by PCOS increased remarkably after the 2000s in China. Combined herbal medicine and western medicine was used the most frequently. RCTs published from 2009 to 2013 were fifty. Average of Jadad score of RCTs was 1.2. Combined herbal medicine and western medicine was also the most frequently used as intervention in RCTs.
Conclusions: Clinical studies on effect of combined herbal medicine and western medicine for infertility caused by PCOS were mostly published in China. But Quality of studies was generally low. Further research on effect of herbal treatment for infertility caused by PCOS is needed.
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KEYWORD
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Polycystic Ovary Syndrome, PCOS, Infertility, Herbal Medicine, RCT
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